Digoxin Monitoring Guidelines. Clinical staff should monitor the plasma digoxin level at least 6 hours or 12 hours postadministration of the last loading dose as this is the time to achieve steadystate levels Recommended thresholds of therapeutic serum digoxin levels are between 05 to 2.
Before StartingOngoing Once StableAbnormal ResultsBibliographyElectrolyte imbalancesHypokalaemia hypomagnesaemia and hypercalcaemia predispose the patient to digoxin related problems and hypokalaemia and hypomagnesaemia should be corrected either orally or intravenously as appropriate Hypocalcaemia may indicate that magnesium levels are also lowThyroid functionInitial and maintenance doses of digoxin should be amended when thyroid function is abnormal.
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Digoxinspecific antibody fragments are safe and effective in severe toxicity Monitoring should continue after treatment because of the small risk of rebound toxicity Restarting therapy should take into account the indication for digoxin and any reasons why the concentration became toxic.
Digoxin Prescribing information Atrial fibrillation
PDF file When monitoring digoxin blood levels should be drawn no sooner than 6 hours after the most recent dose Digoxin levels should be interpreted and acted on based on clinical signs and symptoms Therapeutic digoxin levels should fall between 06 – 12 nmol/L despite reference ranges of up to 26 nmol/L.
Contemporary Use of Digoxin in the Management of
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